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. Author manuscript; available in PMC: 2011 May 17.
Published in final edited form as: Genomics. 2009 Mar 11;93(6):543–550. doi: 10.1016/j.ygeno.2009.02.007

Figure 6. Hairpin structures reduce SNP sensitivity.

Figure 6

All probe sequences were examined for potential to form secondary structures. In some cases, multiple structures of varying stability are predicted for a single sequence. The change in free energy (dG) indicates relative hairpin stability. Probes were classified as containing a hairpin, or containing no hairpins across a range of free energy cutoffs. The probes that span a SNP in the hairpin stem give the lowest sensitivity at all free energies.