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. Author manuscript; available in PMC: 2011 May 18.
Published in final edited form as: Hepatology. 2009 Aug;50(2):434–442. doi: 10.1002/hep.22980

Fig. 5.

Fig. 5

Pharmacologic inhibition of Dgat1 mRNA prevents hepatic steatosis in mice fed a high-fat diet. (A) Real-time PCR analysis of Dgat1 and Dgat2 mRNA after treatment with control or Dgat1 anisense oligonucleotides (ASO), administered twice weekly (50 mg/kg intraperitoneally). *P<0.01 vs. control. (B) Hepatic triglyceride content after 1 week of high-fat diet after pretreatment with control or Dgat1 ASO (n=5). *P<0.05 vs. control.