Abstract
The GenBank sequence database has undergone an expansion in data coverage, annotation content and the development of new services for the scientific community. In addition to nucleotide sequences, data from the major protein sequence and structural databases, and from U.S. and European patents is now included in an integrated system. MEDLINE abstracts from published articles describing the sequences provide an important new source of biological annotation for sequence entries. In addition to the continued support of existing services, new CD-ROM and network-based systems have been implemented for literature retrieval and sequence similarity searching. Major releases of GenBank are now more frequent and the data are distributed in several new forms for both end users and software developers.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. Basic local alignment search tool. J Mol Biol. 1990 Oct 5;215(3):403–410. doi: 10.1016/S0022-2836(05)80360-2. [DOI] [PubMed] [Google Scholar]
- Benson D., Boguski M., Lipman D., Ostell J. The National Center for Biotechnology Information. Genomics. 1990 Feb;6(2):389–391. doi: 10.1016/0888-7543(90)90583-g. [DOI] [PubMed] [Google Scholar]
- Burks C., Cinkosky M. J., Fischer W. M., Gilna P., Hayden J. E., Keen G. M., Kelly M., Kristofferson D., Lawrence J. GenBank. Nucleic Acids Res. 1992 May 11;20 (Suppl):2065–2069. doi: 10.1093/nar/20.suppl.2065. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gish W., States D. J. Identification of protein coding regions by database similarity search. Nat Genet. 1993 Mar;3(3):266–272. doi: 10.1038/ng0393-266. [DOI] [PubMed] [Google Scholar]
- Sikela J. M., Auffray C. Finding new genes faster than ever. Nat Genet. 1993 Mar;3(3):189–191. doi: 10.1038/ng0393-189. [DOI] [PubMed] [Google Scholar]