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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Pain. 2011 Feb 5;152(6):1256–1262. doi: 10.1016/j.pain.2011.01.005

Table 1.

Weighted estimates of characteristics of persons using opioids long-term for chronic non-cancer pain by time-scheduled and pain-contingent dosing status. Limited to persons with 155+ days of pain in the prior 6 months.

Variable A. Pain- contingent dosing only B. Time- scheduled dosing only p-value A vs. B Both A and B Neither A nor B All persons

Sample size (unweighted) (Weighted percent) 325 (25.6 %) 967 (44.8 %) 180 (9.5 %) 309 (20.1%) 1781 (100.0 %)

Female (%) 67.7 % 59.5 % p=.053 49.7 % 71.4 % 63.1 %

Mean age 53.6 56.6 p=.006 54.5 55.5 55.6

Body Mass Index 32.1 30.9 p=0.10 31.3 29.6 31.0

Some college education (%) 58.7 % 63.9 % p=.24 51.8 % 59.3 % 60.5 %

Ever had a drug or alcohol problem (%) 16.9 % 25.4% p=0.02 24.4% 15.1 % 21.0 %

Depression (PHQ-8) 9.4 9.3 p=0.89 8.8 8.9 9.2

Mean days with pain in prior 6 months 179.5 179.7 p=.44 179.8 179.2 179.5

Using opioids for more than one pain condition (%) 67.1 % 66.1 % p=.81 59.3 % 62.0 % 64.9 %

Mean number of days used opioids in the prior two weeks 11.7 13.9 p<.0001 13.5 12.5 13.0

Mean number of times per day used opioids 2.5 3.1 p<.0001 2.5 2.9 2.9

Mean opioid dose prior 3 months (SD) 37.2 (71.2) 97.2 (148.3) p<.0001 74.8 (133.8) 60.9 (174.4) 71.9 (142.8)

Opioid dose level
 < 20 mg/day 46.3 % 18.2 % p<.0001 31.6 % 38.1 % 30.6 %
 20 to < 50 mg/day 36.5 % 32.6 % 35.9 % 35.6 % 35.6 %
 50 to <120 mg/day 12.1 % 29.0 % 19.3 % 15.5 % 15.5 %
 120+ mg/day 5.2 % 20.3 % 13.1 % 10.9 % 13.8 %

Average pain intensity 5.9 5.8 p=.43 5.9 5.8 5.8

Opioids rated as very/extremely helpful (%) 51.1 % 56.9 % p=.20 64.8 % 60.7 % 56.9 %

Predominate use of long- acting opioids in the prior 3 months (%) 11.4 % 43.2 % p<.0001 31.4 % 14.8 % 28.3 %