Table 2. Similarity of structure and sequence between Orf6* and other P450s.
| P450 namea | PDBb code | Z-score | RMSDc Å | Sequence identity % | FGd conformation relative to Orf6* |
|---|---|---|---|---|---|
| OxyB | 1lg9 | 44.9 | 2.2 | 38 | Open |
| CYP105 (MES) | 2z36 | 44.8 | 1.9 | 32 | Same |
| OxyC | 1ued | 44.7 | 2.1 | 37 | Open |
| CYP105P1 (FLI) | 3aba | 43.8 | 2.5 | 36 | Close |
| CYP105P1 (PIM) | 3e5k | 43.6 | 2.0 | 35 | Same |
| P450nor | 1rom | 43.4 | 2.0 | 26 | Same |
| CYP105P1 | 3e5j | 43 | 2.1 | 35 | Same |
| CYP105D6 | 3abb | 42.8 | 1.9 | 33 | Same |
a
P450s that show the highest structural similarity to Orf6*. Shown in parenthesis are bound substrates/ligands. MES: 2-(N-morpholino)-ethanesulfonic acid; FLI: Filipin I; PIM: 4-Phenyl-1H-imidazole.
b
Protein Data Bank.
c
Root mean square deviation.
d
F and G helices of the corresponding P450s.