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. 1992 Feb 11;20(3):421–423. doi: 10.1093/nar/20.3.421

The acceptor stem in pre-tRNAs determines the cleavage specificity of RNase P.

P S Holm 1, G Krupp 1
PMCID: PMC310402  PMID: 1371348

Abstract

As the result of an unusual RNase P specificity, some special, mature tRNAs have acceptor stems with eight instead of the common seven base pairs. The data from numerous studies suggest that some features in the tRNA domain of pre-tRNAs are important for this behaviour. Here, we show that only five base pairs in the acceptor stem of bacterial histidine tRNAs are required to obtain the changed cleavage site in an unrelated eukaryotic serine tRNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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