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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Neuropharmacology. 2011 Mar 21;61(1-2):112–120. doi: 10.1016/j.neuropharm.2011.03.014

Figure 2.

Figure 2

Inhibition of monoamine uptake. Wild type mNET (A) or mDAT (B) were transiently expressed in cultured cells. [3H] labeled norepinephrine or dopamine added to the cells in the presence of increasing concentration of cocaine, RTI-31 and RTI-113. The amount of substrate uptake was determined by scintillation counting. RTI-113 is significantly more potent at inhibiting substrate uptake for mDAT than mNET (p < 0.001, n = 6).