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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Stroke. 2011 Apr 28;42(6):1722–1729. doi: 10.1161/STROKEAHA.110.600106

Table 3.

DALYs[3,1] saved for a 100 patient-years treatment in each trial

Population Composite
endpoint
Nonfatal stroke Nonfatal MI Vascular death
Group 1
   EAFT Stroke 46.96 61.46 4.32 −18.81
   NASCET Stroke 37.62 30.78 NR 6.84
   CURE CHD 21.42 2.75 10.83 7.84
Group 2
   ESPS-2 Stroke 11.58 11.36 −0.15 0.38
   TRITON-TIMI 38 CHD 9.17 0.01 9.75 −0.59
   PROGRESS Stroke 8.79 6.74 1.56 0.49
   ESPRIT Stroke 8.51 3.91 0.46 4.13
   HOPE Primary prevention 7.70 1.56 0.90 5.24
   CARE CHD 6.65 2.20 2.07 2.38
   TASS Stroke 5.84 6.06 NR −0.23
Group 3
   SPARCL Stroke 4.48 2.45 1.91 0.13
   TNT CHD 4.10 1.14 1.47 1.49
   CAPRIE_Stroke Stroke 4.16 3.53 0.38 0.24
   UK-TIA Stroke 2.98 3.94 1.20 −2.16
   SCOPE Primary prevention 2.69 1.91 −0.31 1.09
Group 4
   WHI Primary prevention −1.11 −0.60 −0.34 −0.17
   WEST Stroke −5.53 2.09 −0.89 −6.73
   WASID Stroke −6.47 15.38 −1.41 −20.45

NR: not reported