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. Author manuscript; available in PMC: 2011 Jun 14.
Published in final edited form as: Bioanalysis. 2010 Mar;2(3):469–485. doi: 10.4155/bio.10.14

Figure 14. Quantitation of UPLC eluent fractions of a parent compound and its metabolites are shown by the solid line.

Figure 14

The cumulative sum of the quantified fractions (dashed line) is compared with the direct measure of the labeled compound in the injectate. The LLOQ was found as ten-times the uncertainty in the 14C concentration of the added carrier compound.