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. 1986 Oct 24;14(20):8007–8025. doi: 10.1093/nar/14.20.8007

A family of DNA sequences is reproducibly rearranged in the somatic nucleus of Tetrahymena.

B A Allitto, K M Karrer
PMCID: PMC311831  PMID: 2877440

Abstract

A small family of DNA sequences is rearranged during the development of the somatic nucleus in Tetrahymena. The family is defined by 266 bp of highly conserved sequence which restriction mapping, hybridization and sequence analysis have shown is shared by a cloned micronuclear fragment and three sequences which constitute the macronuclear family. Genomic Southern hybridization experiments indicate there are five members of the family in micronuclear DNA. All of the family members are present in whole genome homozygotes and are therefore nonallelic. The three macronuclear sequences are all present in clonal cell lines and are reproducibly generated in every developing macronucleus. The rearrangement event begins 14 hours after conjugation is initiated and is nearly completed by 16 hours.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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