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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Bone. 2011 Apr 3;48(6):1362–1369. doi: 10.1016/j.bone.2011.03.773

Figure 5. Osteoclasts in the endplate of OPG−/− mice.

Figure 5

(A) TRAP staining of vertebral body 28-week-old of OPG−/− mice and WT littermates (x40). Arrows indicate osteoclasts invading into cartilage matrix. (B) mRNA expression of trap, rank, mmp9 and cathepsin K in RNA extracted from IVD and endplate cartilages of WT and OPG−/− mice at 12, 20 and 28-week-old. Values are the mean ± SD of 3 independent experiments. *p <0.05 vs WT group.