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. 1990 Oct;58(10):3434–3437. doi: 10.1128/iai.58.10.3434-3437.1990

Genetically engineered S and F1C fimbriae differ in their contribution to adherence of Escherichia coli to cultured renal tubular cells.

R Marre 1, B Kreft 1, J Hacker 1
PMCID: PMC313672  PMID: 1976115

Abstract

Escherichia coli K-12 strains producing S-fimbrial adhesins, F1C fimbriae, and mutagenized fimbriae were tested in a binding assay with a renal tubular cell line. S-fimbrial adhesins and F1C fimbriae mediated binding to tubular cells. The SfaA, SfaG, and SfaS subunits of S fimbriae contributed to attachment. Site-specific mutations in the sfaS gene reduced binding. The inhibition profile of F1C fimbriae resembled that of S fimbriae.

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Selected References

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