Table 1.
Elicited utilities of the joint outcomes and values of YE used to compute πT (YE, c, q, β) when efficacy is monitored in 15-minute intervals. Efficacy is defined as the time to blood clot being dissolved, and the adverse event is symptomatic intra-cerebral hemorrhage (SICH), evaluated at 48 hours. The category “> 120” corresponds to the clot not being dissolved by the end of the 120 minute infusion
|
Time Required to Dissolve the Blood Clot |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Minutes | 0 | 1-15 | 16-30 | 31-45 | 46-60 | 61-75 | 76-90 | 91-105 | 106-120 | > 120 |
|
Elicited Utilties
|
||||||||||
| No SICH | 100 | 95 | 90 | 85 | 80 | 75 | 70 | 60 | 50 | 30 |
| SICH | 7 | 6.5 | 6 | 5 | 4.5 | 4 | 2 | 1 | 0 | 0 |
|
Value of YE Used to Compute πT(YE, c, q, β) |
||||||||||
| 0 | .125 | .250 | .375 | .500 | .625 | .750 | .875 | 1.00 | 1.00 | |