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Genotypic determinants predicting coreceptor use by HIV-1 subtype D viruses
| Criteria observed in V3 | No. of Bulk Sequences with the Indicated Phenotype (TTT) | ||
|---|---|---|---|
| 11/25 Amino Acids | Net charge | R5 | R5X4/X4 |
| "R" or "K" at 11 | < +5 | 0 | 0 |
| ≥ +5 | 0 | 2* | |
| "K" at 25 | < +5 | 4 | 1 |
| = +5 | 2 | 0 | |
| > +5 | 0 | 0 | |
| "R" at 25 | < +5 | 1 | 0 |
| ≥ +5 | 1 | 3* | |
| No "R" or "K" at 11 or 25 | < +6 | 14 | 0 |
| ≥ +6 | 0 | 0 | |
*The two viruses harboring an arginine at position 11 have also an arginine at position 25.
