Abstract
Hunt, D. E. (Charles V. Chapin Hospital, Providence, R.I.). Amino acids as protective compounds in ultraviolet-irradiated Hansenula wingei. J. Bacteriol. 88:893–895. 1964.—”Prefeeding” Hansenula wingei with small concentrations of either tryptophan, cystine, tyrosine, phenylalanine, leucine, cysteine, threonine, isoleucine, ethionine, norvaline, or histidine protected this yeast against inactivating ultraviolet treatment. ”Prefeeding” with methionine, proline, or alanine conferred little if any protection, and valine or serine caused this organism to be more sensitive to ultraviolet inactivation. A direct relation exists between the concentration of the protective amino acids and the number of surviving cells. The heterocyclic and aromatic amino acids are generally more protective than the corresponding aliphatic compounds. The diversity of the compounds as well as quantitative differences in the protection afforded by them suggest that they have different modes of action.
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Selected References
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- BERGER H., HASS F. L., WYSS O., STONE W. S. Effect of sodium azide on radiation damage and photoreactivation. J Bacteriol. 1953 May;65(5):538–543. doi: 10.1128/jb.65.5.538-543.1953. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ELLISON S. A., ERLANGER B. F., ALLEN P. The chemical reversal of ultraviolet effects on bacteria. J Bacteriol. 1955 May;69(5):536–540. doi: 10.1128/jb.69.5.536-540.1955. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HEINMETS F., LEHMAN J. J. Preliminary studies on the restoration of viability of ultraviolet-inactivated bacteria by metabolites and cofactors. Arch Biochem Biophys. 1955 Dec;59(2):313–325. doi: 10.1016/0003-9861(55)90497-5. [DOI] [PubMed] [Google Scholar]
- HEINMETS F., LEHMAN J. J., TAYLOR W. W., KATHAN R. H. The study of factors which influence metabolic reactivation of the ultraviolet inactivated Escherichia coli. J Bacteriol. 1954 May;67(5):511–522. doi: 10.1128/jb.67.5.511-522.1954. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HEINMETS F. Reactivation of ultraviolet inactivated Escherichia coli by pyruvate. J Bacteriol. 1953 Oct;66(4):455–457. doi: 10.1128/jb.66.4.455-457.1953. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEIF W. R., HEBERT J. E. Effect of urocanic acid and dipicolinic acid on bacteria exposed to ultraviolet radiation. Am J Hyg. 1960 May;71:285–291. doi: 10.1093/oxfordjournals.aje.a120112. [DOI] [PubMed] [Google Scholar]
- PEACOCK M. G., NAKAMURA M. CHEMICAL PROTECTION AND CHEMORESUSCITATION OF ULTRAVIOLET-IRRADIATED SHIGELLA SONNEI. J Bacteriol. 1963 Jul;86:161–162. doi: 10.1128/jb.86.1.161-162.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SHIMAZU F., TAPPEL A. L. SELENOAMINO ACIDS: DECREASE OF RADIATION DAMAGE TO AMINO ACIDS AND PROTEINS. Science. 1964 Jan 24;143(3604):369–371. doi: 10.1126/science.143.3604.369. [DOI] [PubMed] [Google Scholar]
- THOMPSON T. L., MEFFERD R. B., Jr, WYSS O. The protection of bacteria by pyruvate against radiation effects. J Bacteriol. 1951 Jul;62(1):39–44. doi: 10.1128/jb.62.1.39-44.1951. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WAINWRIGHT S. D., NEVILL A. Modification of the biological effects of ultraviolet irradiation by post-irradiation treatment with iodoacetate and peptone: with an appendix on an interpretation of the effects of post-irradiation treatments based on a chemical model. J Gen Microbiol. 1955 Feb;12(1):1–12. doi: 10.1099/00221287-12-1-1. [DOI] [PubMed] [Google Scholar]