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Serum IgG2a (Th1 isotype) and IgG1 (Th2 isotype) response to H.pylori measured by ELISA. The IgG1 response in male E2 treated, H.pylori-infected INS-GAS mice was significantly higher than that observed in sera from infected intact or castrated mice. Values represent the mean ± standard error. *P < 0.05.
