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. 1968 Jun;95(6):1993–1999. doi: 10.1128/jb.95.6.1993-1999.1968

Bordetella pertussis-induced Alteration of the Normal Hyperglycemic Response of Mice to 3′,5′-Adenosine Phosphate

Lois S Cronholm 1, Charles W Fishel 1
PMCID: PMC315124  PMID: 4299372

Abstract

Blockade of the adrenergic receptors or the injection of Bordetella pertussis vaccine prevented the normal hyperglycemic response of CFW mice to exogenous cyclic 3′,5′-adenosine phosphate (3′,5′-AMP). The cyclic nucleotide was also ineffective in offsetting the histamine hypersensitivity of the β-adrenergically blocked and the pertussis-sensitized groups. These observations suggest that the autonomic malfunction occurs at a point(s) subsequent to release of 3′,5′-AMP. Neither the hyperglycemic effect of epinephrine or 3′,5′-AMP, or both, nor the histamine sensitivity of pertussis-pretreated animals was influenced by the subcutaneous administration of theophylline.

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1993

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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