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. 1969 Jun;98(3):1087–1097. doi: 10.1128/jb.98.3.1087-1097.1969

Chromosomal Location of Genes Regulating Resistance to Bacteriophage in Bacillus subtilis1

F E Young a,2, C Smith a, B E Reilly a,3
PMCID: PMC315300  PMID: 4977981

Abstract

Many of the viruses which infect Bacillus subtilis require glucosylated polyglycerol teichoic acid for adsorption. These mutants can be divided into three classes on the basis of enzymatic defects and growth on galactose-minimal medium. Transduction with phage PBS1 reveals that two of these, gtaA and gtaB, are linked to hisA1, whereas the gtaC locus is linked to argC. Analysis by deoxyribonucleic acid-mediated transformation indicates that these loci exist in a cluster between the hisA1 and argC4 loci. Anomalies in mapping in the group II region of the chromosome exist. The basis of these anomalies is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANAGNOSTOPOULOS C., CRAWFORD I. P. Transformation studies on the linkage of markers in the tryptophan pathway in Bacillus subtilis. Proc Natl Acad Sci U S A. 1961 Mar 15;47:378–390. doi: 10.1073/pnas.47.3.378. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CSISZAR K., IVANOVICS G. TRANSDUCTION IN BACILLUS SUBTILIS. Acta Microbiol Acad Sci Hung. 1965;12:73–89. [PubMed] [Google Scholar]
  3. Curtiss R., 3rd Ultraviolet-induced genetic recombination in a partially diploid strain of Escherichia coli. Genetics. 1968 Jan;58(1):9–54. doi: 10.1093/genetics/58.1.9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Demerec M., Adelberg E. A., Clark A. J., Hartman P. E. A proposal for a uniform nomenclature in bacterial genetics. Genetics. 1966 Jul;54(1):61–76. doi: 10.1093/genetics/54.1.61. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Dubnau D., Goldthwaite C., Smith I., Marmur J. Genetic mapping in Bacillus subtilis. J Mol Biol. 1967 Jul 14;27(1):163–185. doi: 10.1016/0022-2836(67)90358-0. [DOI] [PubMed] [Google Scholar]
  6. Eisenstark A., Eisenstark R., Cunningham S. Genetic analysis of thymineless(thy) mutants in Salmonella typhimurium. Genetics. 1968 Apr;58(4):493–506. doi: 10.1093/genetics/58.4.493. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hoch J. A., Barat M., Anagnostopoulos C. Transformation and transduction in recombination-defective mutants of Bacillus subtilis. J Bacteriol. 1967 Jun;93(6):1925–1937. doi: 10.1128/jb.93.6.1925-1937.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hunter B. I., Yamagishi H., Takahashi I. Molecular weight of bacteriophage PBS 1 deoxyribonucleic acid. J Virol. 1967 Aug;1(4):841–842. doi: 10.1128/jvi.1.4.841-842.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Masters M., Pardee A. B. Sequence of enzyme synthesis and gene replication during the cell cycle of Bacillus subtilis. Proc Natl Acad Sci U S A. 1965 Jul;54(1):64–70. doi: 10.1073/pnas.54.1.64. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Nester E W, Schafer M, Lederberg J. Gene Linkage in DNA Transfer: A Cluster of Genes Concerned with Aromatic Biosynthesis in Bacillus Subtilis. Genetics. 1963 Apr;48(4):529–551. doi: 10.1093/genetics/48.4.529. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Rogolsky M., Slepecky R. A. The response of sporogenesis in Bacillus subtilis to acriflavine. Can J Microbiol. 1968 Jan;14(1):61–64. doi: 10.1139/m68-010. [DOI] [PubMed] [Google Scholar]
  12. SEAMAN E., TARMY E., MARMUR J. INDUCIBLE PHAGES OF BACILLUS SUBTILIS. Biochemistry. 1964 May;3:607–613. doi: 10.1021/bi00893a001. [DOI] [PubMed] [Google Scholar]
  13. Spizizen J., Reilly B. E., Evans A. H. Microbial transformation and transfection. Annu Rev Microbiol. 1966;20:371–400. doi: 10.1146/annurev.mi.20.100166.002103. [DOI] [PubMed] [Google Scholar]
  14. Spizizen J. TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE. Proc Natl Acad Sci U S A. 1958 Oct 15;44(10):1072–1078. doi: 10.1073/pnas.44.10.1072. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Stewart C. R. Mutagenesis by acridine yellow in Bacillus subtilis. Genetics. 1968 May;59(1):23–31. doi: 10.1093/genetics/59.1.23. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. TAKAHASHI I. Genetic transduction in Bacillus subtilis. Biochem Biophys Res Commun. 1961 Jun 28;5:171–175. doi: 10.1016/0006-291x(61)90104-8. [DOI] [PubMed] [Google Scholar]
  17. Taylor A. L., Trotter C. D. Revised linkage map of Escherichia coli. Bacteriol Rev. 1967 Dec;31(4):332–353. doi: 10.1128/br.31.4.332-353.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. YOSHIKAWA H., SUEOKA N. Sequential replication of Bacillus subtilis chromosome. I. Comparison of marker frequencies in exponential and stationary growth phases. Proc Natl Acad Sci U S A. 1963 Apr;49:559–566. doi: 10.1073/pnas.49.4.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. YOSHIKAWA H., SUEOKA N. Sequential replication of the Bacillus subtilis chromosome. II. Isotopic transfer experiments. Proc Natl Acad Sci U S A. 1963 Jun;49:806–813. doi: 10.1073/pnas.49.6.806. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. YOUNG F. E., SPIZIZEN J. Physiological and genetic factors affecting transformation of Bacillus subtilis. J Bacteriol. 1961 May;81:823–829. doi: 10.1128/jb.81.5.823-829.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Yoshikawa H. Mutations Resulting from the Transformation of BACILLUS SUBTILIS. Genetics. 1966 Nov;54(5):1201–1214. doi: 10.1093/genetics/54.5.1201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Young F. E. Requirement of glucosylated teichoic acid for adsorption of phage in Bacillus subtilis 168. Proc Natl Acad Sci U S A. 1967 Dec;58(6):2377–2384. doi: 10.1073/pnas.58.6.2377. [DOI] [PMC free article] [PubMed] [Google Scholar]

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