Table 1.

IAPP immunostaining for pancreatic islets from type 1 diabetics

	Large Islets						Medium Islets
	Total Islet	% Ins	% Glu	% SRIF	% IAPP	% IAPP/Ins	Total Islet	% Ins	% Glu	% SRIF	% IAPP	% IAPP/Ins
Case 1. 18/M	51.2	15.7	66.5	19	18.2	154	18.8	15.4	52.4	32.2	19.8	125
Case 2. 35/F	75.1	0	66.6	33.5	8.5	NC	23	0	61.1	38.8	15.7	NC
Case 3. 39/M	50	0	67.2	32.8	12.1	NC	18.2	0	63.8	36.2	16.7	NC
Mean (n = 3)	58.2	5.2	66.7	28.4	12.9	NC	12.9	20	5.1	59.2	35.7	NC
SE	8.2	5.2	0.2	4.7	2.8	NC	1.5	2.7	3.4	1.9	1.2	NC
Case 4. 43/F	57.6	37.6	46.6	16.5	16.7	44.4	27.8	41	43	16.4	20.8	52
Case 5. 50/F	82	38.3	46.3	15.4	18.3	49.9	30.5	43	39.5	17.2	31	67.6
Case 6. 52/F	80.9	44.2	43.3	13.4	24.9	68.5	30.1	40.3	44.7	14.4	11.7	74.6
Ex large	123.5	42.5	46.8	10	19.7	48.8
Case 7. 61/F	83.1	36.4	35.4	27.7	23.7	59.2	30.7	39.2	33.1	27.9	21.8	57
Ex large	133.5	32.2	39.2	28.2	16.5	51.5
Case 8. 65/F	39	30.7	41.3	27.3	13.3	46.7	22.4	28	49.1	22..4	15	60.3
Case 9. 75/F	87.1	32.8	51	16.6	15.5	52.4	21	35.8	39.7	24.4	26.8	74.7
Ex large	115.4	32.2	53.9	14.2	12.2	43.1
Case 10. 77/F	71.8	39.8	48.9	10.7	20.4	52.1	22.3	39.7	46.8	13.6	16.7	43
Ex large	121	41	47	11.7	26.7	65.3
Mean (n = 7)	71.6	36.1	44.7	19.6	19	53.3	26.4	38.1	42.2	19.5	20.5	61.2
SE	6.5	2.4	2	3.5	1.6	3.1	1.6	1.8	2	2.1	2.5	4.4
Ex large (n = 4)
Mean	123.2	37	46.7	16	18.7	52.2
SE	3.8	2.7	3	4.1	3	4.7
Controls (n = 8)
Mean	71.3	58.3	29.1	11.4	34	60.8	23.6	57.6	27	14.6	37.8	65.7
SE	7.2	3.1	2.6	1	2.8	6.4	1.5	2.7	2.1	0.7	1.8	3.8

Ins, insulin; Glu, glucagon; S RIF, somtostatin; IAPP, islet amyloid polypeptide; Ex large, extra large islet; NC, not calculable.