Abstract
Schulman, Jerome L. (Cornell University Medical College, New York, N.Y.), and Edwin D. Kilbourne. Induction of partial specific heterotypic immunity in mice by a single infection with influenza A virus. J. Bacteriol. 89:170–174. 1965.—Mice infected 4 weeks previously with influenza A virus were found to be partially immune when challenged with influenza A2 virus. This partial immunity was demonstrated by reduced titers of pulmonary virus, decreased mortality, and less extensive lung lesions. A specific immunological basis for this protection was suggested by the absence of any protection in animals previously infected with influenza B virus when challenged with A2 virus, or in animals previously infected with influenza A virus when challenged with influenza B virus. Parenteral inoculation with inactivated influenza A virus did not induce partial immunity to A2 virus challenge. An accelerated rise of hemagglutinating-inhibiting antibody after A2 virus challenge was demonstrated in animals previously infected with influenza A virus.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- CHOPPIN P. W., TAMM I. Two kinds of particles with contrasting properties in influenza A virus strains from the 1957 pandemic. Virology. 1959 Aug;8:539–542. doi: 10.1016/0042-6822(59)90059-5. [DOI] [PubMed] [Google Scholar]
- Francis T., Salk J. E., Quilligan J. J. Experience with Vaccination Against Influenza in the Spring of 1947: A Preliminary Report. Am J Public Health Nations Health. 1947 Aug;37(8):1013–1016. doi: 10.2105/ajph.37.8.1013. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HENLE W., LIEF F. S. THE BROADENING OF ANTIBODY SPECTRA FOLLOWING MULTIPLE EXPOSURES TO INFLUENZA VIRUSES. Am Rev Respir Dis. 1963 Sep;88:SUPPL–386. doi: 10.1164/arrd.1963.88.3P2.379. [DOI] [PubMed] [Google Scholar]
- JENSEN K. E., DAVENPORT F. M., HENNESSY A. V., FRANCIS T., Jr Characterization of influenza antibodies by serum absorption. J Exp Med. 1956 Aug 1;104(2):199–209. doi: 10.1084/jem.104.2.199. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LIEF F. S., HENLE W. Antigenic analysis of influenza viruses by complement fixation. VI. Implications of age distribution of antibodies to heterologous strains following infection and vaccination. J Immunol. 1960 Nov;85:494–510. [PubMed] [Google Scholar]
- SCHULMAN J. L., KILBOURNE E. D. Induction of viral interference in mice by aerosols of inactivated influenza virus. Proc Soc Exp Biol Med. 1963 Jun;113:431–435. doi: 10.3181/00379727-113-28387. [DOI] [PubMed] [Google Scholar]