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Reduced epithelial AR activation in PE-PTEN+/-IKK2ca/ca. (A) Paraffin sections of wild-type and transgenic tissue (anterior prostate, 12 months) stained for AR with Hoechst counterstain. (B) Quantification for wild-type and transgenic tissues (n = 4 each). (C) Quantitative PCR of androgen-responsive gene Probasin (n = 6 per group). Scale bars, 50 µm. **P < .01; *P < .05.
