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(A) Time-course of gadolinium concentration (mM) calculated from the T1 time in the jugular vein (A), kidney (B) and liver (C) of PEG2k-PAMAM(G5) (red), PEG5k-PAMAM(G4) (black), PEG2k-PAMAM(G4) (blue) and Ac-PAMAM (G4) (green). (D) Clearance rate (mMGd/min) from blood pool.