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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Hypertension. 2011 Aug 1;58(3):446–453. doi: 10.1161/HYPERTENSIONAHA.111.177006

Figure 6.

Figure 6

Thrombin-induced SMC migration and proliferation are Nox1-dependent. (A) Summary data of the distance that SMCs migrated after scratch wound in the presence of thrombin. (B) Summary data of SMC migration measured using the modified Boyden chamber method. (C) SMC proliferation was measured by [3H] thymidine incorporation. Data are normalized to control WT cells. (D) Effect of nifedipine on migration of WT SMCs was measured as in (B). Data are reported as % change from WT control. (E) Effect of sodium vanadate on migration of Nox1 null SMCs was measured as in (B). Data are reported as % change from WT control. For A-D, * P< 0.05 vs. WT control; ‡ P< 0.05 vs. WT + thrombin. For E, * P<0.05 vs. WT control; ‡ P< 0.05 vs. Nox1 null + thrombin. Data represent means ± SEM of 3-4 experiments in duplicate.