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. 1966 May;91(5):1971–1976. doi: 10.1128/jb.91.5.1971-1976.1966

Comparative Study of Seven Picornaviruses of Man

Richard M Jamison 1, Heather D Mayor 1
PMCID: PMC316153  PMID: 4287079

Abstract

Jamison, Richard M. (Baylor University College of Medicine, Houston, Tex.), and Heather D. Mayor. Comparative study of seven picornaviruses of man. J. Bacteriol. 91:1971–1976. 1966.—The buoyant densities in CsCl and potassium tartrate of seven acid-resistant picornaviruses of man were determined. The viruses studied were found to be a relatively homogeneous group. Buoyant densities ranged from 1.32 to 1.35 g/cc in CsCl and 1.21 to 1.23 g/cc in potassium tartrate. The buoyant density of each virus did not vary by more than 0.01 g/cc. The host cell of origin and passage level did not influence the buoyant density of the virions. However, measurements of the diameters of purified virions by a standard method have shown that there are considerable size variations among these picornaviruses. The diameters ranged from 18 to 25 mμ. Echovirus 19 and poliovirus 1 were significantly larger (mean diameter, 23.5 mμ) than echoviruses 4, 6, 16, and 23, and coxsackievirus B2 (mean diameter, 21.0 mμ).

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Selected References

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  1. BARRON A. L., KARZON D. T. Characteristics of ECHO 4 (Shropshire) virus isolated during epidemic of aseptic meningitis. J Immunol. 1961 Nov;87:608–615. [PubMed] [Google Scholar]
  2. BRENNER S., HORNE R. W. A negative staining method for high resolution electron microscopy of viruses. Biochim Biophys Acta. 1959 Jul;34:103–110. doi: 10.1016/0006-3002(59)90237-9. [DOI] [PubMed] [Google Scholar]
  3. HALL C. E. Electron densitometry of stained virus particles. J Biophys Biochem Cytol. 1955 Jan;1(1):1–12. doi: 10.1083/jcb.1.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. HALPEREN S., EGGERS H. J., TAMM I. COMPLETE AND CORELESS HEMAGGLUTINATING PARTICLES PRODUCED IN ECHO 12 VIRUS-INFECTED CELLS. Virology. 1964 May;23:81–89. doi: 10.1016/s0042-6822(64)80010-6. [DOI] [PubMed] [Google Scholar]
  5. JAMISON R. M., MAYOR H. D., MELNICK J. L. Studies on ECHO 4 virus (Picornavirus group) and its intracellular development. Exp Mol Pathol. 1963 Apr;2:188–202. doi: 10.1016/0014-4800(63)90052-2. [DOI] [PubMed] [Google Scholar]
  6. KARZON D. T., POLLOCK B. F., BARRON A. L. Phase variation in ECHO virus type 6. Virology. 1959 Dec;9:564–576. doi: 10.1016/0042-6822(59)90149-7. [DOI] [PubMed] [Google Scholar]
  7. MELNICK J. L., RHIAN M., WARREN J., BREESE S. S., Jr The size of Coxsackie viruses and Lansing poliomyelitis virus determined by sedimentation and ultra filtration. J Immunol. 1951 Aug;67(2):151–162. [PubMed] [Google Scholar]
  8. Plummer G. The picornaviruses of man and animals: a comparative review. Prog Med Virol. 1965;7:326–361. [PubMed] [Google Scholar]
  9. ROIZMAN B., ROANE P. R., Jr A physical difference between two strains of herpes simplex virus apparent on sedimentation in cesium chloride. Virology. 1961 Sep;15:75–79. doi: 10.1016/0042-6822(61)90079-4. [DOI] [PubMed] [Google Scholar]
  10. SCHAFFER F. L., FROMMHAGEN L. H. SIMILARITIES OF BIOPHYSICAL PROPERTIES OF SEVERAL HUMAN ENTEROVIRUSES AS SHOWN BY DENSITY GRADIENT ULTRACENTRIFUGATION OF MIXTURES OF THE VIRUSES. Virology. 1965 Apr;25:662–664. doi: 10.1016/0042-6822(65)90095-4. [DOI] [PubMed] [Google Scholar]
  11. SCHWERDT C. E., SCHAFFER F. L. Some physical and chemical properties of purified poliomyelitis virus preparations. Ann N Y Acad Sci. 1955 Sep 27;61(4):740-50; discussion, 750-3. doi: 10.1111/j.1749-6632.1955.tb42530.x. [DOI] [PubMed] [Google Scholar]
  12. WALLIS C., MELNICK J. L. A rapid method for production of replicate monkey kidney tissue cultures in unstoppered tubes. Tex Rep Biol Med. 1960;18:670–673. [PubMed] [Google Scholar]
  13. WIGAND R., SABIN A. B. Properties of ECHO types 22, 23 and 24 viruses. Arch Gesamte Virusforsch. 1961;11:224–247. doi: 10.1007/BF01241688. [DOI] [PubMed] [Google Scholar]

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