Figure 5. HPA Axis Hyperactivity following CeA CRF-OE (Experiment-1).
LVCRFp3.0CRF led to an increase in plasma ACTH concentrations in the Sal/Sal group (B) and the Dex/CRF group) (D). LVCRFp3.0CRF also produced a significant increase in plasma corticosterone in the Dex/CRF group (C) but not the Sal/Sal group (A). (One-tailed T-test analysis based on the a-priori hypothesis that increased CeA CRF would increase HPA axis reactivity * p < 0.05; ** p < 0.01; *** p< 0.001).