Table II.

Association of GSTM1, GSTT1 deletion and prostate cancer in populations of African descent according to smoking habits

	Controls (N)	Cases (N)	Adjusted ORa (95% CI)
GSTM1 (null versus present)
Never-smokersb	920	785	0.87 (0.77–0.97)
Ever smokersc	817	769	1.03 (0.91–1.15)
Pack × years
≤4.7	137	114	0.86 (0.63–1.18)
4.8–10	142	93	1.19 (0.87–1.87)
10–24	128	148	1.19 (0.89–1.58)
>24	132	166	1.02 (0.78–1.34)
African-American
Never-smokers	95	90	0.66 (0.46–0.95)
Ever smokers	223	243	1.28 (1.01–1.56)
Caribbean
Never-smokers	786	668	0.89 (0.79–1.01)
Ever smokers	960	498	0.94 (0.81–1.09)
African
Never-smokers	33	21	0.56 (0.24–1.31)
Ever smokers	27	23	0.50 (0.14–1.86)
GSTT1 (null versus present)
Never- Smokersd	887	744	0.84 (0.75–0.94)
Ever smokerse	810	764	0.91 (0.80–1.02)
Pack × years
≤4.7	130	113	0.99 (0.74–1.33)
4.8–10	132	87	0.89 (0.64–1.24)
10–24	109	137	0.77 (0.56–1.05)
>24	104	135	1.30 (0.94–1.79)
African-American
Never-smokers	68	56	0.99 (0.61–1.60)
Ever smokers	159	181	0.83 (0.65–1.05)
Caribbean
Never-smokers	786	668	0.84 (0.77–0.95)
Ever smokers	556	498	0.93 (0.81–1.07)
African
Never-smokers	33	19	0.58 (0.26–1.33)
Ever smokers	27	23	0.77 (0.36–1.65)

^aAdjusted for study and age (quartiles).

^bInteraction GSTM1 × ethnicity: P = 0.38.

^cInteraction GSTM1 × ethnicity: P = 0.05.

^dInteraction GSTT1 × ethnicity: P = 0.79.

^eInteraction GSTT1 × ethnicity: P = 0.38.