Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells

Correction to: British Journal of Cancer (2011) 104, 948–956; doi:10.1038/bjc.2011.54

When published originally, earlier this year in Volume 104, the authors noticed a couple of errors in the Results section.

The first is in the subheading entitled ‘Selection of peptide- and ET-specific T cells’. In the second paragraph of this subsection, on page 951, the second sentence should read ‘For example, of the T cells initially specifically selected with the CHM1³¹⁹/HLA-A^*0201-multimer, 96 cell lines were grown and tested for specific IFN-γ release against CHM1³¹⁹ peptide.’

The legend of Figure 4 should read ‘Low granzyme B responses against HLA class I blocked A673 and HLA-A^*0201⁺ PBMC compared with unblocked A673.’

Figure 4.

Low granzyme B responses against HLA class I blocked A673 and HLA-A^*0201⁺ PBMC compared with unblocked A673. HLA class I blocking before granzyme B ELISpots caused reversion of specific recognition by CHM1³¹⁹ or EZH2⁶⁶⁶ peptide specific CD8⁺ T cells at an effector to target (E/T) ratio of 5:1. Granzyme B release upon contact with irradiated OKT3-stimulated/unstimulated HLA-A^*0201⁺ PBMC remained low compared with unblocked A673 at the same E/T ratio. Asterisks indicate significance levels of A673 lysis compared with respective controls (two-tailed t-test, ^*P<0.05; ^**P<0.01).

The publishers and authors are now happy to correct these errors.