SUMMARY
A cohort of endogenous depressives and normal controls were studied to examine the role of DST in depressives treated with ECT. Weekly DST estimation was done and depression was assessed on HRS-D. 73.6% patients were found to be non suppressors as compared to controls in whom 16.7% were non suppressors. 60% DST positive patients showed clinical improvement while 50% DST negative did not show improvement. This proves the notion that DST is a state dependent biological marker of endogenous depressed state.
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