Fig. 2.

Summary of the actions of NFI proteins and their effector target genes during CGN development. Different events subject to NFI regulation in maturing CGNs are shown on the left, along with a portrayal of the developmental pattern of NFI protein expression. The temporal patterns of expression for currently identified NFI target genes are shown by vertical bars on the right. The NFI targets N cadherin (Ncad) and ephrin B1 regulate axon formation and fasciculation via homotypic cell interactions, as well as CGN migration and dendritogenesis. Tag-1, Wnt-7a, and Gabra6 exhibit more restricted expression patterns and have more selective functions either in pre-migratory or post-migratory CGNs