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. 1989 Jun 12;17(11):4293–4308. doi: 10.1093/nar/17.11.4293

Monoadduct forming photochemical reagents for labeling nucleic acids for hybridization.

J P Albarella 1, R L Minegar 1, W L Patterson 1, N Dattagupta 1, E Carlson 1
PMCID: PMC317935  PMID: 2500642

Abstract

We describe the synthesis of three angelicin derivatives which can be used for labeling nucleic acids with biotin. These compounds were used to label nucleic acids in the presence of lysed cell constituents. The resulting labelled nucleic acids show hybridization to a genus specific probe for E. coli. The relative comparison of sensitivity indicates that a polyamine linker is better than a polyethylene oxide linker between the biotin and angelicin moieties.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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