In Tzeng et al. (2011), in Table 2, the coefficients of determination for the normalised conductance model were presented in error. The correct values are shown in the table below. This error does not alter the interpretation or discussion in the text.
Table 2.
Parameter estimates between control and Ca2+ channel blockade condition during 0.05 and 0.10 Hz OLBNP
0.10 Hz | 0.05 Hz | 2 × 2 RMANOVA | |||||
---|---|---|---|---|---|---|---|
Control | Blockade | Control | Blockade | Freq | Con | Freq × Con | |
Windkessel model | |||||||
Capacitive gain (cm mmHg−1) | 1.7 ± 0.30 | 1.8 ± 0.58 | 1.6 ± 0.87 | 1.4 ± 0.60 | 0.23 | 0.94 | 0.40 |
Conductive gain (cm s−1 mmHg−1) | 0.022 ± 0.077 | 1.8 ± 0.58 | −0.008 ± 0.21 | 0.20 ± 0.35 | 0.60 | <0.05 | 0.28 |
R2 | 0.99 ± 0.016 | 0.99 ± 0.0097 | 0.91 ± 0.065 | 0.89 ± 0.068 | — | — | — |
Normalised Windkessel model | |||||||
Capacitive gain (% s−1 mmHg−1) | 2.3 ± 0.45 | 2.9 ± 0.87 | 2.4 ± 1.2 | 2.3 ± 0.93 | 0.38 | 0.58 | 0.22 |
Conductive gain (% mmHg−1) | 0.11 ± 0.36 | 0.13 ± 0.10 | −0.038 ± 0.32 | 0.27 ± 0.51 | 0.96 | <0.05 | 0.26 |
R2 | 0.97 ± 0.03 | 0.99 ± 0.0044 | 0.91 ± 0.069 | 0.89 ± 0.067 | — | — | — |
Conductance model | |||||||
Conductive gain (cm s−1 mmHg−1) | 0.82 ± 0.32 | 0.96 ± 0.35 | 0.21 ± 0.32 | 0.48 ± 0.40 | <0.05 | <0.05 | 0.17 |
R2 | 0.53 ± 0.23 | 0.64 ± 0.22 | 0.34 ± 0.31 | 0.42 ± 0.33 | — | — | — |
Normalised conductance model | |||||||
Conductive gain (% mmHg−1) | 1.1 ± 0.35 | 1.5 ± 0.49 | 0.31 ± 0.47 | 0.71 ± 0.52 | <0.05 | <0.05 | 0.91 |
R2 | 0.57 ± 0.25 | 0.64 ± 0.22 | 0.34 ± 0.31 | 0.42 ± 0.33 | — | — | — |
Freq, frequency; Con, drug condition; Freq × Con, interaction.
Reference
- Tzeng YC, Chan GS, Willie CK, Ainslie PN. Determinants of human cerebral pressure–flow velocity relationships: new insights from vascular modelling and Ca2+ channel blockade. J Physiol. 2011;589:3263–3274. doi: 10.1113/jphysiol.2011.206953. [DOI] [PMC free article] [PubMed] [Google Scholar]