TABLE 1. UW-Madison renal transplants from deceased donors, 1993–2007.
Transplant type | |||||
---|---|---|---|---|---|
Local >0MM | Local 0MM | Shipped >0MM | Shipped 0MM | P | |
n | 1310 | 29 | 181 | 264 | — |
Recipient age (yr) | 48.7±13.4 | 51.4±14.3 | 49.8±13.8 | 48.0±12.2 | 0.3 |
Donor age (yr) | 42.5±17.5 | 36.5±16.9 | 38.75±18.7 | 34.7±14.9 | <0.001 |
Tx No. | 1.25±0.5 | 1.28±0.53 | 1.15±0.44 | 1.48±0.77 | <0.001 |
Recipient BMI (kg/m2) | 26.6±6.6 + 5.3 | 32.74±18.7 | 27.2±5.9 | 26.8±5.4 | 0.06 |
Donor BMI (kg/m2) | 28.5±7.9 | 27.74±5.65 | 27.93±7.2 | 27.1±6.8 | 0.62 |
ESRD (mo) | 14.8±11.6 | 19.5±12.3 | 13.4±10.8 | 17.3 ±11.9 | <0.001 |
Peak PRA | 12.75±23.3 | 17.6±29.6 | 7.6±17.4 | 25.4±34.0 | <0.001 |
Cold storage time (hr) | 2.98±6.4 | 5.6±9.1 | 14.4±8.4 | 12.2±7.4 | <0.001 |
Total preservation time (hr) | 22.5±6.9 | 21.4±5.9 | 25.1 ±5.9 | 23.2±5.9 | <0.001 |
Race (% white) | |||||
Recipients | 79.8 | 93.1 | 77.3 | 94.3 | <0.001 |
Donors | 94.7 | 96.6 | 80.4 | 94.7 | <0.001 |
Gender (% male) | |||||
Recipients | 58.7 | 62.1 | 61.3 | 61.7 | 0.75 |
Donors | 60.3 | 72.4 | 54.7 | 59.5 | 0.27 |
High PRA (% ≥20) | 17.6 | 27.6 | 8.8 | 35.2 | <0.001 |
Diabetes (%) | 24.7 | 44.8 | 24.9 | 32.6 | 0.006 |
Donor type (% SCD) | 45.9 | 51.7 | 53.6 | 52.7 | 0.07 |
Induction immunosuppression | |||||
Steroids (%) | 99.9 | 100 | 100 | 99.6 | 0.46 |
Calcineurin inhibitors (%) | <0.001 | ||||
Cyclosporine | 55.9 | 55.2 | 63.0 | 56.4 | |
Tacrolimus | 25.0 | 31.0 | 21.0 | 36.0 | |
None | 19.1 | 13.8 | 16.0 | 7.6 | |
Antiproliferatives (%) | 0.6 | ||||
Azathioprine | 14.7 | 6.9 | 17.7 | 11.7 | |
Mycophenolate | 82.7 | 89.7 | 81.8 | 85.6 |
UW-Madison, University of Wisconsin, Madison; 0MM, 0-mismatch; Tx, transplant; BMI, body mass index; ESRD, end-stage renal disease; PRA, panel reactive antibodies.