Skip to main content
. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Biomaterials. 2011 Aug 27;32(33):8343–8355. doi: 10.1016/j.biomaterials.2011.05.001

Fig 6.

Fig 6

Migration of human macrophages through SMP and the Universal placebo (a & c) undiluted and (b & d) on with vaginal fluid simulant (VFS) as a function of time. Macrophages were tagged with cell tracker dye and the migration of the macrophages through the polymer network was monitored by collecting z-stacks at 1 h intervals between times 0 to 4 h. Unlike the Universal placebo gel, the PBA-SHA SMP demonstrated complete inhibition of macrophage diffusion through the crosslinked polymer network, independent of dilution with VFS. Figures on the right illustrate the fluorescence intensity distribution as function of depth and time, thereby offering a quantitative measure of macrophage migration in the polymers.