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. 1989 Sep 12;17(17):6939–6945. doi: 10.1093/nar/17.17.6939

Characterization of 5' truncated transposed copies of the I factor in Drosophila melanogaster.

I Busseau 1, A Pelisson 1, A Bucheton 1
PMCID: PMC318424  PMID: 2550903

Abstract

I factors in Drosophila melanogaster are transposable elements structurally related to Mammalian LINEs. Their transposition is activated at high frequencies during I-R hybrid dysgenesis and is associated with the production of mutations of various sorts. Very few of these mutations have been studied at the molecular level; those reported so far result either from chromosomal rearrangements or from insertions of complete I factors. We have analysed three I-R induced yellow mutations and have found that one of them is due to the insertion of an I element very similar to the complete I factor, whereas the other two are due to insertions of I elements that are truncated at their 5' ends; one of them exhibits an unusual 3' end. We discuss possible mechanisms of production of such modified I elements.

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Selected References

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