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. 2011 Jun 3;3(6):677–713. doi: 10.3390/v3060677

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© 2011 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 1. — Proviral genome structure of the Murine Leukemia Virus (MLV), a simple retrovirus. Indicated are the 5′ and 3′ long terminal repeat (LTR; open boxes) regions comprising U3, R and U5, as well as open reading frames (filled boxes) for gag, pol and envelope (env) proteins. Processed protein subunits are indicated in bold. att, attachment site; cap, 5′RNA capping site; pA, polyadenylation site; PBS, primer binding site; SD, splice donor; ψ, packaging signal; SA, splice acceptor; PPT, polypurine tract; MA, matrix; CA, capsid; NC, nucleocapsid; PR, protease; RT, reverse transcriptase; IN, integrase; SU, surface; TM, trans-membrane; E, enhancer; P, promoter.