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. 1984 May 25;12(10):4051–4061. doi: 10.1093/nar/12.10.4051

In situ activation of bis-dialkylaminophosphines--a new method for synthesizing deoxyoligonucleotides on polymer supports.

A D Barone, J Y Tang, M H Caruthers
PMCID: PMC318815  PMID: 6728676

Abstract

Deoxynucleoside phosphoramidites can be prepared in good yield from deoxynucleosides, bis- dialkylaminophosphines , and the corresponding dialkylamine hydrotetrazolide or tetrazole as catalysts. These phosphoramidites generated in situ lead to the direct synthesis of deoxyoligonucleotides on polymer supports.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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