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. 2011 Oct 6;343:d5694. doi: 10.1136/bmj.d5694

Table 1.

 Combinations of screening and interventions for the control of meticillin resistant Staphylococcus aureus (MRSA) in patients on intensive care units

Screening Screening method Intervention
Patient group* Timing Procedure
No screening Conventional culture of clinical swabs only MRSA positive On result Isolation or decolonisation (chlorhexidine)
No screening Conventional culture of clinical swabs only All patients Pre-emptively Isolation or decolonisation (chlorhexidine)
No screening Conventional culture of clinical swabs only High risk patients Pre-emptively Isolation or decolonisation (chlorhexidine)
All patients Conventional culture High risk patients Pre-emptively (amended on screen result) Isolation†
All patients on admission, and weekly thereafter Conventional culture MRSA positive On result Isolation or decolonisation (mupirocin)
Chromogenic agar MRSA positive On 48 hour result Isolation or decolonisation (mupirocin)
MRSA positive On 24 hour result (amended on 48 hour result) Isolation†
Polymerase chain reaction MRSA positive On result Isolation or decolonisation (mupirocin)
High risk patients on admission, and weekly thereafter Conventional culture MRSA positive On result Isolation or decolonisation (mupirocin)
Chromogenic agar MRSA positive On 48 hour result Isolation or decolonisation (mupirocin)
MRSA positive On 24 hour result (amended on 48 hour result) Isolation†
Polymerase chain reaction MRSA positive On result Isolation or decolonisation (mupirocin)

In all strategies, if MRSA was recovered from a clinical specimen the patient was isolated or decolonised according to the specified intervention.

*MRSA positive patients are believed to be colonised or infected with MRSA based on clinical or screening swab result.

†Decolonisation not applicable.