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. 1981 May;78(5):3147–3150. doi: 10.1073/pnas.78.5.3147

Genes in mice that affect susceptibility to cortisone-induced cleft palate are closely linked to Ir genes on chromosomes 2 and 17.

D L Gasser, L Mele, D D Lees, A S Goldman
PMCID: PMC319517  PMID: 6942422

Abstract

Inbred and congeneic strains of mice have been examined for susceptibility to cortisone-induced cleft palate, and the role of genes linked to H-2 on chromosome 17 has been confirmed. Increasing degrees of susceptibility were associated with the H-2d, H-2b, H-2k, and H-2a haplotypes, respectively, with H-2q and H-2s also being associated with fairly high levels of susceptibility. Evidence was obtained that suggests that one gene maps within the B region of H-2, and that a second H-2 linked gene which acts by complementation maps to the right of E. Another gene affecting this trait is closely linked to the H-3 and Ir-2 loci on the second chromosome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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