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. 1981 Jul;78(7):4256–4260. doi: 10.1073/pnas.78.7.4256

Pyochelin: novel structure of an iron-chelating growth promoter for Pseudomonas aeruginosa.

C D Cox, K L Rinehart Jr, M L Moore, J C Cook Jr
PMCID: PMC319768  PMID: 6794030

Abstract

Pyochelin, an endogenous growth promoter that solubilizes ferric iron, has been isolated from Pseudomonas aeruginosa, including clinical strains. The structure of pyochelin has been assigned as 2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid and is of a different type from those previously assigned to siderophores (siderochromes) from bacteria. The assignment rests on 1H and 13C NMR data, high-resolution (including field desorption) mass spectrometry, and spectroscopic properties of synthetic model compounds. Pyochelin is presumed to be biosynthesized from salicylic acid and two moles of cysteine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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