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. Author manuscript; available in PMC: 2012 Oct 25.
Published in final edited form as: Biochemistry. 2011 Sep 27;50(42):9014–9022. doi: 10.1021/bi201307u

Figure 1.

Figure 1

Sequence alignment of the juxtamembrane domain regions of human syntaxins. The alignment (generated in BioEdit (44) using a database of SNAREs (26)) reveals a conserved polybasic region that is most pronounced in family members that are targeted to the plasma membrane. The final layers of the four-helical bundle making up the SNARE core complex and the entire transmembrane domains concluding with the C-termini are also shown flanking the juxtamembrane regions.