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. 1984 Jul 25;12(14):5927–5941. doi: 10.1093/nar/12.14.5927

Nuclear magnetic resonance study of d-TGGCCA in solution.

E Guittet, D Piveteau, J Y Lallemand, T Huyn-Dinh, J Igolen
PMCID: PMC320041  PMID: 6462922

Abstract

The 1H NMR spectrum of a self complementary deoxyhexanucleotide (d-TGGCCA) in water solution has been completely and unambiguously assigned by use of two-dimensional techniques and phosphorus off-resonance decoupling experiments. The helix-coil transition has been monitored by following most of the non-exchangeable protons against temperature and was shown to be a cooperative dissociation-association process. Sequential fraying is sizable even at low temperature. Considerations of coupling constants and of Nuclear Overhauser effects show the helix to be of the B-DNA type.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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