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. 1981 Aug;78(8):5000–5004. doi: 10.1073/pnas.78.8.5000

Periodic synthesis of microtubular proteins in the cell cycle of Physarum.

T G Laffler, M T Chang, W F Dove
PMCID: PMC320319  PMID: 6946448

Abstract

Periodic polypeptide labeling over the naturally synchronous nuclear replication cycle of Physarum polycephalum was analyzed by fluorography of two-dimensional electropherograms. Two sets of polypeptides, denoted as P and Q, showed strong periodicity; they were maximally labeled just prior to mitosis. This periodicity was shown to reflect synthesis rather than turnover or recovery. Both P and Q copolymerized with porcine microtubular proteins and displayed electrophoretic properties similar to those of porcine tubulins. The significance of the periodic synthesis of these microtubular proteins is discussed as a possible component within the chain of events that establishes the high mitotic synchrony of Physarum syncytia.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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