Figure 6.
Computer simulations of the DNA bound RSCt species fractions present at different total nucleotide concentrations. A mathematical estimation of DNA bound to the RSCt as a function of nucleotide concentration was performed by using the Monte Carlo simulation using the experimental data as the input; Panel (A) is for ADP and Panel (B) is for AMP-PNP. It is clearly visible that in presence of ADP a significant portion of RSCt is present as the DNA bound species while as in presence of AMP-PNP most of the protein is unbound at higher concentrations.