Table 2.
Cytology Category with Incidence of Malignancy, and Final Histopathology
| Cytology category | No. of patients | Malignant, na(%) | Histopathology of malignant tumors in primary FNA target nodule [%] | Occurrence of IPC, n (%) | Histopathology of benign neoplasms in primary FNA target nodule |
|---|---|---|---|---|---|
| S-FN | 226 | 37 (16) | PC=18 (included 7 FV-PTC) [49%]; FC=15 [40%], HCC=3 [8%] Other (metastasis of RCC in a FA)=1 [3%] | 10b (4.4) | FA=134 FA-HCF=5 HCA=13 HPN=38 |
| S-HCN | 100 | 14 (14) | PC=2 [14%]; FC=2 [14%]; HCC=10 [72%] | 5 (5) | HCA=53 FA-HCF=14 FA=2 Other=16c |
| S-PC | 126 | 96 (76) | PC=93 (including 16 FV of PC) [97%]; FC=2; MC=1 | N/A | N/A |
| S-Other | 10 | 5 (50) | Lymphoma=3; MC=2 | N/A | N/A |
Does not include cases of IPC listed in final column.
Includes one patient with coexisting HCC and IPC.
Includes a variety of benign nonneoplastic findings.
N/A, not applicable; IPC, incidental papillary carcinoma (seen in nodule other than target of FNAB); S-FN, suspicious for follicular neoplasm; S-HCN, suspicious for Hürthle cell neoplasm; S-PC, suspicious for papillary carcinoma; S-Other, suspicious for other (includes lymphoma, MC, and atypical); FC, follicular carcinoma; HCC, Hürthle cell carcinoma; MC, medullary carcinoma, FV, follicular variant; RCC, renal cell carcinoma; HCA, Hürthle cell adenoma; FA, follicular adenoma. HCF, Hürthle cell features; HPN, Hyperplastic nodules; FNAB, fine-needle aspiration biopsy.