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. 1982 Sep 25;10(18):5599–5604. doi: 10.1093/nar/10.18.5599

Correlation between glycosyl torsion angle and sugar ring pucker does not always exist.

J N Low, P Tollin, H R Wilson
PMCID: PMC320909  PMID: 7145709

Abstract

A survey of the conformational parameters of deoxypyrimidine nucleosides and nucleotides shows that the correlation between glycosyl torsion angle and sugar pucker, which has often been considered to be well-established, does not always exist. This may be of significance when interactions between DNA and other molecules are considered.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Altona C., Sundaralingam M. Conformational analysis of the sugar ring in nucleosides and nucleotides. A new description using the concept of pseudorotation. J Am Chem Soc. 1972 Nov 15;94(23):8205–8212. doi: 10.1021/ja00778a043. [DOI] [PubMed] [Google Scholar]
  2. Arnott S., Chandrasekaran R., Birdsall D. L., Leslie A. G., Ratliff R. L. Left-handed DNA helices. Nature. 1980 Feb 21;283(5749):743–745. doi: 10.1038/283743a0. [DOI] [PubMed] [Google Scholar]
  3. Arnott S., Hukins D. W. Conservation of conformation in mono and poly-nucleotides. Nature. 1969 Nov 29;224(5222):886–888. doi: 10.1038/224886a0. [DOI] [PubMed] [Google Scholar]
  4. Berman H. M., Neidle S., Stodola R. K. Drug-nucleic acid interactions: conformational flexibility at the intercalation site. Proc Natl Acad Sci U S A. 1978 Feb;75(2):828–832. doi: 10.1073/pnas.75.2.828. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Camerman N., Fawcett J. K., Cameran A. Molecular structure of a deoxyribose-dinucleotide, sodium thymidylyl-(5' yields to 3')-thymidylate-(5') hydrate (pTpT), and a possible structural model for polythymidylate. J Mol Biol. 1976 Nov 15;107(4):601–621. doi: 10.1016/s0022-2836(76)80086-1. [DOI] [PubMed] [Google Scholar]
  6. Drew H. R., Wing R. M., Takano T., Broka C., Tanaka S., Itakura K., Dickerson R. E. Structure of a B-DNA dodecamer: conformation and dynamics. Proc Natl Acad Sci U S A. 1981 Apr;78(4):2179–2183. doi: 10.1073/pnas.78.4.2179. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HARRIS D. R., MACINTYRE W. M. THE CRYSTAL AND MOLECULAR STRUCTURE OF 5-FLURO-2'-DEOXY-BETA-URIDINE. Biophys J. 1964 May;4:203–225. doi: 10.1016/s0006-3495(64)86778-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Haschemeyer A. E., Sobell H. M. The crystal structure of a hydrogen bonded complex of deoxyguanosine and 5-bromodeoxycytidine. Acta Crystallogr. 1965 Jul 10;19(1):125–130. doi: 10.1107/s0365110x65002864. [DOI] [PubMed] [Google Scholar]
  9. Holbrook S. R., Sussman J. L., Warrant R. W., Kim S. H. Crystal structure of yeast phenylalanine transfer RNA. II. Structural features and functional implications. J Mol Biol. 1978 Aug 25;123(4):631–660. doi: 10.1016/0022-2836(78)90210-3. [DOI] [PubMed] [Google Scholar]
  10. Jack A., Ladner J. E., Klug A. Crystallographic refinement of yeast phenylalanine transfer RNA at 2-5A resolution. J Mol Biol. 1976 Dec 25;108(4):619–649. doi: 10.1016/s0022-2836(76)80109-x. [DOI] [PubMed] [Google Scholar]
  11. Jain S. C., Tsai C. C., Sobell H. M. Visualization of drug-nucleic acid interactions at atomic resolution. II. Structure of an ethidium/dinucleoside monophosphate crystalline complex, ethidium:5-iodocytidylyl (3'-5') guanosine. J Mol Biol. 1977 Aug 15;114(3):317–331. doi: 10.1016/0022-2836(77)90253-4. [DOI] [PubMed] [Google Scholar]
  12. Sakore T. D., Jain S. C., Tsai C. C., Sobell H. M. Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex. Proc Natl Acad Sci U S A. 1977 Jan;74(1):188–192. doi: 10.1073/pnas.74.1.188. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Seeman N. C., Day R. O., Rich A. Nucleic acid-mutagen interactions: crystal structure of adenylyl-3',5'-uridine plus 9-aminoacridine. Nature. 1975 Jan 31;253(5490):324–327. doi: 10.1038/253324a0. [DOI] [PubMed] [Google Scholar]
  14. Tsai C. C., Jain S. C., Sobell H. M. Visualization of drug-nucleic acid interactions at atomic resolution. I. Structure of an ethidium/dinucleoside monophosphate crystalline complex, ethidium:5-iodouridylyl (3'-5') adenosine. J Mol Biol. 1977 Aug 15;114(3):301–315. doi: 10.1016/0022-2836(77)90252-2. [DOI] [PubMed] [Google Scholar]
  15. Viswamitra M. A., Reddy B. S., Lin G. H., Sundaralingam M. Stereochemistry of nucleic acids and their constituents. XVII. Crystal and molecular structure of deoxycytidine 5'-phosphate monohydrate. A possible puckering for the furanoside ring in B-deoxyribonucleic acid. J Am Chem Soc. 1971 Sep 8;93(18):4565–4573. doi: 10.1021/ja00747a038. [DOI] [PubMed] [Google Scholar]
  16. Wilson H. R. Changes in nucleoside conformation. Nature. 1970 Feb 7;225(5232):545–545. doi: 10.1038/225545a0. [DOI] [PubMed] [Google Scholar]

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