TABLE 1.

Quantification of calcium imaging of dispersed β-cells isolated from control and ABCA1^−P/−P mice

Variable	ABCA1+/+	n	ABCA1−P/−P	n	P
Basal [Ca2+]i ratio	0.343 ± 0.004	18	0.368 ± 0.006	17	0.0002
Response to
Glucose (10 mmol/L)
Peak ratio	1.324 ± 0.044	10	1.258 ± 0.017	9	0.197
Area under the curve	3.542 ± 0.212	10	2.916 ± 0.135	9	0.027
Tolbutamide (100 μmol/L)
Peak ratio	1.313 ± 0.036	5	1.183 ± 0.055	4	0.078
Area under the curve	2.621 ± 0.126	5	2.213 ± 0.093	4	0.042
KCl (30 mmol/L)
Peak ratio	1.528 ± 0.059	10	1.400 ± 0.047	10	0.105
Area under the curve	3.943 ± 0.136	10	3.429 ± 0.162	10	0.024

Data are presented as mean ± SE.