Table 3.
Random allocation | Intention to treat | Per protocol | ||||||
---|---|---|---|---|---|---|---|---|
MI N = 183 | No MI N = 187 | Unadjusted OR (95% CI) | Adjusted * OR (95% CI) | Adjusted ** OR (95% CI) | Adjusted ** OR (95% CI) | |||
Baseline n (%) | 3 months n (%) | Baseline n (%) | 3 months n (%) | |||||
Primary outcome | ||||||||
Hazardous drinking over previous month | 129 (70.5) | 87 (47.5) | 138 (73.8) | 101 (54.0) | 0.77 (0.51,1.16) | 0.79 (0.52,1.19) | 0.64 (0.39,1.06) | 0.53 (0.29,0.97) |
Components of primary outcome | ||||||||
Surrogates over previous month | 22 (12.0) | 9 (4.9) | 25 (13.4) | 11 (5.9) | 0.83 (0.33,2.04) | 0.87 (0.31,2.46) | 0.77 (0.23,2.54) | 0.23 (0.02,2.32) |
Zapoi over previous month | 30 (16.4) | 13 (7.1) | 33 (17.7) | 13 (6.7) | 1.03 (0.46,2.29) | 1.08 (0.47,2.49) | 0.85 (0.31,2.34) | 0.50 (0.12,2.01) |
Hangover/bed clothed twice or more per week on average over previous month *** | 7 (3.8) | 14 (7.7) | 9 (4.8) | 11 (5.8) | 1.33 (0.59,3.02) | 1.39 (0.61,3.16) | 0.95 (0.37,2.46) | 1.20 (0.39,3.67) |
Average weekly consumption of ethanol over past month > 250 ml | 103 (56.3) | 83 (45.4) | 112 (59.9) | 90 (48.1) | 0.89 (0.59,1.35) | 0.92 (0.60,1.39) | 0.77 (0.47,1.26) | 0.68 (0.37,1.25) |
* adjusted for baseline values of outcome measures (or similar) using analysis of covariance
** additionally adjusted for AUDIT score
*** excessive drinking not asked at 3 month