Table 1.

Prevalence of Substance Use Disorders among Borderline Patients and Axis II Comparison Subjects Over 10 Years of Prospective Follow-up

	Borderline Patients						Axis II Comparison Subjects
	BL (N=290)	2 Yr FU (N=275)	4 Yr FU (N=269)	6 Yr FU (N=264)	8 Yr FU (N=255)	10 Yr FU (N=249)	BL (N=72)	2 Yr FU (N=67)	4 Yr FU (N=64)	6 Yr FU (N=63)	8 Yr FU (N=61)	10 Yr FU (N=60)	Risk Ratio Diagnosis Time	95% CI Diagnosis Time
Any Substance Abuse/Dependence	62.1 (N=180)	29.8 (N=82)	23.8 (N=64)	18.9 (N=50)	15.3 (N=39)	13.7 (N=34)	45.8 (N=33)	14.9 (N=10)	10.9 (N=7)	7.9 (N=5)	13.1 (N=8)	8.3 (N=5)	1.65 0.16	1.28, 2.14 0.19, 0.23
Any Alcohol Abuse/Dependence	50.3 (N=146)	20.4 (N=56)	14.5 (N=39)	11.4 (N=30)	8.6 (N=22)	8.8 (N=22)	38.9 (N=28)	9.0 (N=6)	7.8 (N=5)	4.8 (N=3)	6.6 (N=4)	1.7 (N=1)	1.21 0.03	0.71, 2.06 0.01, 0.19
Any Drug Abuse/Dependence	46.6 (N=135)	20.4 (N=56)	15.2 (N=41)	12.9 (N=34)	9.0 (N=23)	7.2 (N=18)	34.7 (N=25)	10.5 (N=7)	6.3 (N=4)	3.2 (N=2)	8.2 (N=5)	6.7 (N=4)	1.62 0.10	0.98, 2.69 0.03, 0.39
Both Alcohol and Drug Abuse/Dependence	34.5 (N=100)	10.9 (N=30)	6.0 (N=16)	5.3 (N=14)	2.4 (N=6)	2.4 (N=6)	27.8 (N=20)	4.9 (N=3)	3.1 (N=2)	0.0 (N=0)	1.6 (N=1)	0.0 (N=0)	1.52 0.02	1.04, 2.20 0.01, 0.05

P-level results for diagnosis were any substance abuse/dependence, <0.001; any alcohol, .008; any drug, .001; both alcohol and drug, 0.029

P-level results for time were all <0.001