The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton.

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The following grant information should be included. “This work was also supported by the Maine Medical Center Research Institute Histopathology and Bioinformatics Core Facilities, which was supported by National Institutes of Health Grant P20RR18789 (to D. M. Wojchowski), and the Transgenic Mouse Core Facility, which was supported by National Institutes of Health Grant RR015555 (to R. Friesel).”