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. 1986 Jun;83(12):4504–4508. doi: 10.1073/pnas.83.12.4504

Lack of class I H-2 antigens in cells transformed by radiation leukemia virus is associated with methylation and rearrangement of H-2 DNA.

D Meruelo, R Kornreich, A Rossomando, C Pampeno, A Boral, J L Silver, J Buxbaum, E H Weiss, J J Devlin, A L Mellor, et al.
PMCID: PMC323762  PMID: 3012570

Abstract

Transformation of murine thymocytes by radiation leukemia virus is associated with reduced expression of the class I antigens encoded in the major histocompatibility complex (MHC) and increased methylation and altered restriction enzyme patterns of MHC DNA. These changes may play a role in host susceptibility to virus-induced leukemogenesis and accord with the notion that viral genomes play a regulatory function when they integrate adjacent to histocompatibility genes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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